Seattle News

26-01-2026

William Foege, whose vaccination strategy defeated smallpox, dies

Dr. William H. Foege, a legendary figure in global public health, has died at the age of 89. He went down in history as the architect of the strategy that led to the complete eradication of smallpox worldwide — one of medicine's greatest triumphs. Foege was also a key figure in shaping the Bill & Melinda Gates Foundation’s programs, one of the largest private philanthropic organizations in the world, which plays a central role in financing global health initiatives. The foundation is headquartered in Seattle, Bill Gates’s hometown, where a developed ecosystem of technology and biomedical research supports collaboration with local organizations.

His principal contribution was the development of the “ring vaccination” method. Instead of mass-vaccinating entire populations, he proposed identifying and vaccinating people in the immediate contacts of each infected person, thereby creating an “immunological ring.” This targeted and efficient strategy allowed smallpox to be declared eradicated by 1977.

Foege’s career was closely linked with leading global health institutions. In 1977 he took the helm of the U.S. Centers for Disease Control and Prevention (CDC), and later co-founded the international nonprofit organization The Task Force for Global Health. His expert opinion was highly valued at the highest levels.

For his achievements Foege received numerous prestigious awards, including the Presidential Medal of Freedom — the highest civilian honor in the United States. A building at the University of Washington bears his name, a testament to the deep respect for his legacy within the scientific community. That university, among the top research institutions in the U.S. with strong global health programs, honored him in recognition of his outstanding contributions to public health.

Foege’s interest in medicine and science began in childhood. The son of a clergyman and having spent part of his youth in Washington state, he started working in a pharmacy at age 13. This region, with its high-quality education, progressive health policies and network of research centers, creates an environment that fosters the development of specialists in his field. He was strongly influenced by the example of missionary physician and Nobel Peace Prize laureate Albert Schweitzer.

After receiving his medical education at the University of Washington, Foege, contrary to expectations, chose a career not as a practicing physician but as a public health specialist. A decisive factor in that choice was his experience working in the Seattle and King County Department of Health — known in the U.S. for innovative approaches to infectious disease control and promoting health equity — and his subsequent studies at Harvard.

Later, Foege served as executive director of The Carter Center. In a statement, the center noted that under his leadership dracunculiasis (Guinea worm disease) is on the brink of eradication and could become the second disease after smallpox to be wiped off the face of the earth. Former U.S. President Jimmy Carter called Foege a man who saved millions of lives.

Foege also played a key role in shaping the Bill & Melinda Gates Foundation’s global health programs, bringing seriousness and strategic vision to their early work. Dr. Foege leaves behind not only a vast professional legacy but also a family: a wife, children, grandchildren and great-grandchildren.

Based on: William Foege, medical pioneer who helped stamp out smallpox, has died